ESM1 PROMOTE PROLIFERATION, INVASION AND ANGIOGENESIS VIA AKT/MTOR AND RAS PATHWAY IN KIDNEY RENAL CLEAR CELL CARCINOMA

ESM1 promote proliferation, invasion and angiogenesis via Akt/mTOR and Ras pathway in kidney renal clear cell carcinoma

Abstract The most common types of renal carcinoma is kidney renal clear cell carcinoma (KIRC).ESM1 is a secreted protein, which involved in, lipids and glucose metabolism, but their role in angiogenesis is contradictory in different disease, especially in KIRC.Bioinformatic analysis confirmed the ESM1 expression and prognosis in KIRC.IHC staining r

read more

An Eco-Sustainable Stabilization of Clayey Road Subgrades by Lignin Treatment: An Overview and a Comparative Experimental Investigation

Subgrade conditions significantly Oval Bottles affect functionality of the road pavement during its service life.Among the different stabilization techniques for upgrading poorly performing in-situ soil subgrades, an economically attractive example involves the use of waste materials, such as lignin.A deep bibliographic analysis of previous studies

read more

Chain mediations of perceived social support and emotional regulation efficacy between role stress and compassion fatigue: insights from the COVID-19 pandemic

BackgroundNurses at the frontline faced high risks of the COVID-19 infection, undertook heavy workloads of patient care, and experienced tremendous stress that often led to compassion fatigue.AimThis study was to explore the role of positive psychosocial resources (i.e., perceived social support and emotional regulation efficacy) in the relationshi

read more


Individual Tree Segmentation Based on Region-Growing and Density-Guided Canopy 3-D Morphology Detection Using UAV LiDAR Data

Forest tree information is crucial for monitoring forest resources and developing forestry management strategies.Airborne laser scanning is an efficient and rapid method for acquiring 3-D point cloud data of forests, making up for the shortcomings of optical remote sensing.Especially for unmanned aircraft vehicle laser scanning, the high-density po

read more